A survey of urine positivity to 4-aminoquinoline was carried out to examine the current status of the chloroquine in the treatment of malaria in Southwestern, Nigeria. Out of 352 students examined 352(61%) were positive using Dill-Glazko test. High occurrence was more among the primary school pupils (68%), than secondary (62%), and tertiary (47%). More female student (61%) used chloroquine than male (55%). Pupils in the age group 6-10years (26%) had the highest occurrence followed by 11-15years (16%), 16-20years (8%), 21-25years (5%), 1-5years (3%) and 26-30years (1%) respectively. Although, newer antimalarial drugs such as Atesunate/Arthemeter, Halofantrin etc have been introduced lately, more people in Ado-Ekiti still prefer Chloroquine for the treatment of malaria. This result of the study suggests that chloroquine is still the first line of drug for the treatment of malaria in Ekiti state, Southwestern Nigeria.
Some newly heterochelates synthesized by reflux of 3-acetyl 4-hydroxy coumarin, Enrofloxacin and transition metal. 1H, 13C, IR and ESI Mass confirm the formation of ligand. The heterochelates were characterized on the basis of different spectroscopic techniques like IR studies and elemental analysis while the geometry of complexes was octahedral which is confirmed by electronic spectra analysis. The compounds were subjected to antimicrobial, antioxidant and anti-tubercular activity viewing using serial broth dilution method and Minimum Inhibitory Concentration (MIC) is determined.
Gravimetric determination of the Co(II) with the 2-hydroxy,1-napthaldehyde Sulphathiazole. The synthesis of metal sulfanilamide compounds has received much attention due to the effective chemotherapeutic agents to be employed for the prevention and cure of bacterial infections in humans. The present works deals with the synthesis and preliminary characteristics of various Schiff bases as ligands. Schiff bases derived by the condensation 2-hydroxy,1-napthaldehyde with Sulphathiazole. After synthesis of such Schiff bases as ligands, Co+2 ion introduced with them by chelation. The chemical and physical properties of metal chelates evaluated. Antimicrobial properties the ligands and metal chelate of 2-hydroxy,1-napthaldehyde Sulphathiazole also evaluated.
The World Health Organization estimates that a staggering two billion people harbor parasitic worm infections. Parasitic worms also infect livestock and crops, affecting food production with a resultant economic impact. Despite this prevalence of parasitic infections, the research on anthelmintic drug is poor. As per WHO, only few drugs are frequently used in the treatment of helminthes in human beings. Anthelmintic from the natural sources may play a key role in the treatment of this parasitic infections.In the present investigation, anthelmintic screening of crude extracts of Hygrocybe parvula. The present study aimed at the in-vitro evaluation of anthelmintic activity of various solvent extracts of fruiting bodies of H. parvula using at three different concentrations (25, 50 and 100mg/ml) respectively. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. In view of this petroleum ether, chloroform and methanol extracts of fruiting bodies of H. parvula were evaluated separately for the activity on adult Indian earthworms, Pheretima posthuma, using Piperazine citrate as reference standards. The results indicated that the petroleum ether extract was more potent than the chloroform and methanol solvent extract. All extracts showed effective anthelmintic activity at 100mg/ml concentration.
In this paper, a wide study was done on the various nano fillers used in electrical apparatuses. The important physical, chemical, thermal, mechanical and electrical properties of the nano fillers were discussed. The applications of the nano fillers were discussed. This paper would be helpful for the young scientist and engineers to study about the important nano fillers used in the electrical insulation system. This would motivate them for their research work to invent nano electrical and electronic apparatuses.
This paper deals with the basic knowledge for engineers to study about the need for HVDC transmission, applications, advantages, disadvantages, types and basic components of HVDC transmission. In addition, a review was given on the recent trends in HVDC transmission.